Phospho-GSK-3alpha (Ser21) (36E9) Rabbit mAb 9316L from Cell Signaling Technology

Product Specs
ItemPhospho-GSK-3alpha (Ser21) (36E9) Rabbit mAb
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number9316L
Quantity300 µl
ApplicationsW, IHC-P
ReactivityH, M, R, Mk
TargetGSK3-alpha (Ser21) phosphate
ModificationsGSK3-alpha (Ser21) phosphate
HostRabbit
ClonalityMonoclonal
NCBI Full Gene Nameglycogen synthase kinase 3 alpha
Research AreaPI3K / Akt Signaling
Clone36000000000
Molecular Weight51

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Toward countering muscle and bone loss with spaceflight: GSK3 as a potential targetiScienceJuly 21, 2023Ryan W. Baranowski, Jessica L. Braun, Briana L. Hockey, Jenalyn L. Yumol, Mia S. Geromella, Colton J.F. Watson, Nigel Kurgan, Holt N. Messner, Kennedy C. Whitley, Adam J. MacNeil, et al.catenin, MHC I, MHC IIa, MHC IIx, MHC IIb. Antibodies from pGSK3β (9336), total (t)-GSK3-β (9315), pGSK3α (9316), tGSK3α (4818), β-Catenin (8480) were obtained from Cell Signaling Technology (Danvers, MA, USA). MHC

(2) PTEN phosphatase inhibits metastasis by negatively regulating the Entpd5/IGF1R pathway through ATF6iScienceFebruary 17, 2023Yanlin Yu, Meng Dai, Liping Huang, Weiping Chen, Ellen Yu, Arnulfo Mendoza, Helen Michael, Chand Khanna, Marcus Bosenberg, Martin McMahon, et al.RRID:AB_10950969" anti-GSK3α,Cell Signaling,"Cat# 4337, RRID:AB_10859910" anti-phospho-GSK3α(Ser21),Cell Signaling,"Cat# 9316, RRID:AB_659836" anti-GSK3β,Cell Signaling,"Cat# 12456, RRID:AB_2636978" anti-phospho-GSK3β (Ser9),Cell Signaling

(3) Fibroblast GSK-3α Promotes Fibrosis via RAF-MEK-ERK Pathway in the Injured HeartCirculation ResearchSeptember 16, 2022Prachi Umbarkar, Sultan Tousif, Anand P. Singh, Joshua C. Anderson, Qinkun Zhang, Michelle D. Tallquist, James Woodgett, Hind Lal,Santa Cruz Biotechnology,SC-133063 PE,1:100,https://www.scbt.com/p/il-11-antibody-a-9 p-GSK-3α (Ser21),Cell Signaling Technology,9316,1:100,https://www.cellsignal.com/products/primary-antibodies/phospho-gsk-3a-ser21-36e9-rabbit-mab/9316 α-SMA,Sigma-Aldrich,A5228,1:400,https://www.sigmaaldrich.com/US/en/product/sigma/a5228 α-Actinin,Sigma-Aldrich,SAB4503474,1:200,https://www.sigmaaldrich.com/US/en/product/sigma/sab4503474 "Donkey

(4) GSK3β palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axisOncogenesisMay 23, 2022Zhao C, Yu H, Fan X, Niu W, Fan J, Sun S, Gong M, Zhao B, Fang Z, Chen X.methods Antibodies and reagents Antibodies against GSK3β (12456), p-GSK3β (S9) (8566), GSK3α (4337), p-GSK3α (S21) (9316), EZH2 (5246), STAT3 (9139), p-STAT3 (Y705) (9145), β-catenin (8480), AKT1 (4691), and HA (3724) were

(5) Telocytes reduce oxidative stress by downregulating DUOX2 expression in inflamed lungs of miceActa biochimica et biophysica SinicaApril 25, 2022Tang H, Liang T, Zhou Y, Ju H, Song D, Fang H.phosphorylated STAT3 (Ser727) (CST-9134), phosphorylated STAT5 (CST-4322), phosphorylated STAT6 (CST-9316), and GAPDH (CST-5558) were purchased from Cell Signaling Technology. Dual luciferase reporter assay The

(6) Hotspot ESR1 Mutations Are Multimodal and Contextual Modulators of Breast Cancer MetastasisCancer researchApril 1, 2022Li Z, Wu Y, Yates ME, Tasdemir N, Bahreini A, Chen J, Levine KM, Priedigkeit NM, Nasrazadani A, Ali S, et al.AB_10544537), AIF (#5318, RRID: AB_10634755), GSK3β (Ser9, #5558, RRID: AB_10013750), phospho-GSK3α (Ser21, #9316, RRID: AB_659836), GSK3β (#12456, RRID: AB_2636978) and GSK3α (#4337, RRID: AB_10859910) from Cell Signaling Technology

(7) Underlying mechanisms of glucocorticoid-induced Î²-cell death and dysfunction: a new role for glycogen synthase kinase 3Cell Death & DiseaseDecember 7, 2021Etienne Delangre, Junjun Liu, Stefania Tolu, Kamel Maouche, Mathieu Armanet, Pierre Cattan, GaÃ«lle Pommier, Danielle BailbÃ©, Jamileh Movassat(Cell Signaling, Saint-Cyr, France, ref. 9315), anti-pSer21GSK3α (Cell Signaling, Saint-Cyr, France, ref. 9316), anti-GSK3α (Cell Signaling, Saint-Cyr, France, ref. 9338), anti-GR (Cell Signaling, Saint-Cyr, France,

(8) Ser9 phosphorylation of GSK-3β promotes aging in the heart through suppression of autophagyThe Journal of Cardiovascular AgingNovember 15, 2021Yanbin Chen, Yasuhiro Maejima, Akihiro Shirakabe, Takanobu Yamamoto, Yoshiyuki Ikeda, Junichi Sadoshima, Peiyong Zhaiagainst GSK-3α [Cell Signaling Technology (CST), #9338], GSK-3β (CST, #9315), phospho-GSK-3α (S21) (CST, #9316), phospho-GSK-3β (S9) (CST, #9336), β-catenin (CST, #9582), MCL-1 (Rockland, #600–401-394), p62 (Abcam,

(9) Proteomic Analysis of Hydromethylthionine in the Line 66 Model of Frontotemporal Dementia Demonstrates Actions on Tau-Dependent and Tau-Independent NetworksCellsAugust 22, 2021Karima Schwab, Valeria Melis, Charles R. Harrington, Claude M. Wischik, Mandy Magbagbeolu, Franz Theuring, Gernot Riedel(#9206; 1:5000), 4E-BP1 (#9452; 1:1000), p4E-BP1 (#9459; 1:1000), GSK-3α (#4337; 1:1000), p GSK-3α (#9316; 1:1000), GSK-3β (#12456; 1:1000) and p GSK-3β (#5558; 1:1000) all from Cell Signaling Technology Europe,

(10) Akt-mTOR hypoactivity in bipolar disorder gives rise to cognitive impairments associated with altered neuronal structure and functionNeuronMay 1, 2021Amanda M. Vanderplow, Andrew L. Eagle, Bailey A. Kermath, Kathryn J. Bjornson, Alfred J. Robison, Michael E. Cahill,Cell Signaling Technology,"Cat# 9644, RRID:AB_2097841" Phospho-gsk3α S21,Cell Signaling Technology,"Cat# 9316, RRID:AB_659836" p-gsk3ß S9,Cell Signaling Technology,"Cat# 5558, RRID:AB_10013750" GAPDH,Santa Cruz Biotechnology

(11) Use of Pyrolysis Oil from Scrap Tires with Control Module Adjustment of Diesel EngineSensors and MaterialsJanuary 31, 2021Jai-Houng Leu, Ming-Wei Shao, Tian-Syung Lan, Xuan Sun, Chih-Ying Chuangcontent mg/kg 1.384 0.377 0.000 D95 ASTM Sulfur content % 1.15 0.17 0.00 D2622 ASTM Heating value kcal/kg 11567 10578 9316 D240 Kinematic At 40 ℃ ASTM 1.83 3.29 4.56 viscosity cST D445 ASTM Density g/cm3 0.94 0.87 0.94 D1298 ASTM Cetane

(12) A GSK3-SRF Axis Mediates Angiotensin II Induced Endothelin Transcription in Vascular Endothelial CellsFrontiers in cell and developmental biologyJanuary 1, 2021Yang Y, Wang H, Zhao H, Miao X, Guo Y, Zhuo L, Xu Y.5558), anti-GSK3α (Proteintech, 13419-1, Wuhan, China), anti-phospho-Ser21-GSK3α (Cell Signaling Tech, 9316, Danvers, MA, United States), anti-phospho-(S/T)F (Cell Signaling Tech, 9631, Danvers, MA, United States),

(13) GSK3‐ARC/Arg3.1 and GSK3‐Wnt signaling axes trigger amyloid‐β accumulation and neuroinflammation in middle‐aged Shugoshin 1 miceAging CellOctober 1, 2020Chinthalapally V. Rao, Mudassir Farooqui, Avanish Madhavaram, Yuting Zhang, Adam S. Asch, Hiroshi Y. Yamada[T180+Y182] (Bioss, bs‐2210R), p21WAF1/CIP1 (Santa Cruz, sc‐817), p‐GSK3α (S21) (Cell Signaling Technology, #9316), p‐GSK3β (S9) (Biorbyt, # orb393067), p‐TAU(S262) (EnoGene; E011111), p‐TAU (S404) (Santa Cruz, sc‐12952),

(14) GSK-3β Contributes to Parkinsonian Dopaminergic Neuron Death: Evidence From Conditional Knockout Mice and TideglusibFrontiers in Molecular NeuroscienceJune 3, 2020Junyu Li, Shanshan Ma, Jingnan Chen, Kunhua Hu, Yongyi Li, Zeyu Zhang, Zixiang Su, James R. Woodgett, Mingtao Li, Qiaoying Huangroom temperature for 1 h. Primary antibodies against p-GSK-3α Ser21 (Cell Signaling Technology, Cat. #9316, RRID:AB_659836), p-GSK-3β Ser9 (Cell Signaling Technology, Cat. #5558, RRID:AB_10013750), GSK-3α (Abcam, Cat.

(15) An ultrasensitive fiveplex activity assay for cellular kinasesScientific reportsDecember 19, 2019Smolko CM, Janes KA.Ab Kinase,Source,Amount,3x Tag,Protein,Amount,Source,Dilution Akt,Millipore #05-591,20 ng,VSVG,GSK3α(1–97),0.1 µg,CST #9316,1:5000 IKK,CST #2682,220 ng,HA,IκBα(1–62),0.1 µg,R&D #AF4809,1:5000 JNK,SCBT #sc-474,80 ng,GluGlu,c-jun,1

(16) Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular functionFASEB bioAdvancesAugust 1, 2019Hurcombe JA, Lay AC, Ni L, Barrington AF, Woodgett JR, Quaggin SE, Welsh GI, Coward RJ.glomerulus. 2.12 Antibodies Antibodies were obtained from Cell Signalling Technology: (pGSK3α [Ser 21] #9316; pGSK3β [Ser 9] #9323; total GSK3α/β #5676; total GSK3α #9338; pAKT [Ser 473] #4060; total AKT #4691;

(17) Glycogen Synthase Kinase-3α Promotes Fatty Acid Uptake and Lipotoxic CardiomyopathyCell metabolismMay 7, 2019Nakamura M, Liu T, Husain S, Zhai P, Warren JS, Hsu CP, Matsuda T, Phiel CJ, Cox JE, Tian B, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies Anti-rabbit monoclonal phospho-GSK-3α (Ser21) (36E9),Cell Signaling,9316 Anti-rabbit monoclonal GSK-3α (D80E6),Cell Signaling,4337 Anti-rabbit monoclonal GSK-3α (D80D1) XP,Cell Signaling

(18) Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overloadJournal of Molecular and Cellular CardiologyMay 1, 2019Firdos Ahmad, Anand P. Singh, Dhanendra Tomar, Mohamed Rahmani, Qinkun Zhang, James R. Woodgett, Douglas G. Tilley, Hind Lal, Thomas Forceperformed at 1:1,000 dilution for anti-GSK-3α (Cell Signaling# 5676), phospho-GSK-3α (Cell Signaling #9316), Bax (Cell Signaling #2772), Bcl-xL (Cell Signaling #2764), VDAC (Cell Signaling #4661), 1:100 for

(19) White light emitting diode induces autophagy in hippocampal neuron cells through GSK-3-mediated GR and RORα pathwaysAging (Albany NY)March 28, 2019Yang Yang, Yimin Jia, Qinwei Sun, Haibo Dong, Ruqian ZhaoUSA, diluted 1:1000), GSK-3α (9338, Cell Signaling Technology, USA, diluted 1:1000), phospho-GSK-3α (9316, Cell Signaling Technology, USA, diluted 1:1000), GSK-3β (9315, Cell Signaling Technology, USA, diluted

(20) Targeting PRMT5/Akt signalling axis prevents human lung cancer cell growthJournal of cellular and molecular medicineFebruary 1, 2019Zhang S, Ma Y, Hu X, Zheng Y, Chen X.Cell Signaling Technology), GSK3α (cat no. 4337; Cell Signaling Technology), p‐Ser21‐GSKα (cat no. 9316; Cell Signaling Technology), PTEN (cat no. 9559; Cell Signaling Technology), p‐mTOR‐Ser2448 (cat no.

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Phospho-GSK-3alpha (Ser21) (36E9) Rabbit mAb

Phospho-GSK-3alpha (Ser21) (36E9) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-GSK-3alpha (Ser21) (36E9) Rabbit mAb from Cell Signaling Technology

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